Lecture 6 - 9/11: Protein structure and function II
Today's reading: Chapter 2 pp 154-166.
Reading for next lecture: Chapter 2 pp 166-179.
Key words: PRIMARY, SECONDARY, TERTIARY and QUATERNARY PROTEIN STRUCTURE

MOTIFS and DOMAINS
a-HELIX
b-SHEET and b-TURN
COILED-COIL

PROTEIN FAMILIES
SUBUNIT
LIGAND and BINDING SITE
ANTIBODIES

PROTEIN PURIFICATION
HOMOGENIZATION -> CELL EXTRACT
CENTRIFUGATION
ELECTROPHORESIS
STRUCTURE DETERMINATION: X-ray crystallography and NMR spectroscopy