There are two ways to view the various intermediates and cofactors of glycolysis from this page:
First, for each of the 10 glycolytic reactions shown schematically at the left, a click on the reaction number will display the substrate (in this frame) and the product (in the frame to the right); a summary of the reaction and additional information will be displayed in the reaction frame (above). In this way, the models can be viewed in the context of the overall pathway.
Second, any pair of molecules can be viewed by making a choice from the selection forms currently shown in the reaction frame (after scrolling). These lists include nucleotides and other cofactors that do not appear in the displays of the 10 reactions.
Note: the reaction arrows only indicate the direction of the glycolytic pathway. A table of
G°' values is shown
in the reaction frame, however, you should consult your text for details on the energetics
of each reaction (e.g. reversibility under physiological conditions etc. ). Most of the frames have Chime buttons that highlight a structural feature. For example, the button in the adjacent frame will highlight different portions of the ATP molecule.
Note the different size scales in the images and recall that a carbon-carbon single bond is about 1.5Å. In several cases, buttons provide a distance measure for the models.
Links to additional information for the reactions are indicated as red text in some display frames. As demonstrated with this link, capsule information will sometimes be displayed in the window status line at the bottom of the page when the mouse is over a link. For example, put your mouse over the "-" next to an abbreviation on the "Pathway of Carbon" to read the complete name of the intermediate.
Some NETSCAPE navigation tips:
· To go back to any image you have already seen, click on the title (blue) text within the then current frame and choose "Back in Frame". (Choosing "Back" from the "Go" menu list will take you to the last URL you visited; but do come back!)
· Return to this introduction page with its two molecule-selection forms by choosing "Reload" from the "View" menu with the "option" key down ("Super Reload").
·The appropriate width for this page is about nine inches.
Back to Molecular Models for Biochemistry at CMU.
Dr. William McClure wm0p@andrew.cmu.edu. Department of Biological Sciences Carnegie Mellon University Pittsburgh, PA 15213