Research Interests
1. Medicinal Plants. Plants, mainly from the family Labiatae
and Scrophulariaceae families, are being examined to isolate and characterize
the major natural products. Identification of metabolites and biological
activity is an integral part of this project.
2. Microbial transformations. Natural products of agricultural
and pharmaceutical interest are chemically modified by selected strains of fungi
in an effort to produce a range of new analogues with enhanced bioactivity.
3. Steroids. Partial synthesis of steroid hormones is studied
with the aim of identifying cheaper routes to the production of these costly
biochemicals.
Selected publications
- P.B. Reese, J.R. Hanson, J.A. Takahashi and M.R. Wilson,
"Biotransformation of some Stemodane Diterpenoids by Cephalosporium
aphidicola", Phytochemistry, 1994, 36, 1391.
- P.B. Reese, P.L. Ruddock, "An unexpected product from the reaction of
Mercury(II) Trifluoroacetate with 3-substituted Steroids", Journal of
Chemical Research (S), 1994, 442.
- P.B. Reese, R.B.R. Porter, L.A.D. Williams, and D.J. Williams, "Acaricidal
and insecticidal activities of Cadina-4,10(15)-dien-3-one",
Phytochemistry, 1995, 40, 735
- P.B. Reese and R.J. Lancashire. Microwave Oven Reaction Enhanced (MORE)
preparation of stilbenediamines. Electronic Conference on Trends in Organic
Chemistry (ECTOC-1), Eds. H.S. Rzepa and J. G. Goodman (CD-ROM), Royal Society
of Chemistry publications, 1995. See a copy here or
the other ECTOC papers held
at Imperial College.
- P.B. Reese, P.L. Ruddock, D.J. Williams, "The scope and limitations of the
reaction of D5 -steroids with mercury(II)
trifluoroacetate", Steroids, 1998, 63, 650.
Created and maintained by Dr.
Robert J. Lancashire,
The Department of Chemistry, University of the West
Indies,
Mona Campus, Kingston 7, Jamaica.
Created Feb 1995. Last modified 3rd June, 1999.
URL
http://wwwchem.uwimona.edu.jm:1104/chpr.html