(5E,13E)-9,15-DIHYDROXY-11-OXOPROSTA-5,13-DIEN-1-OIC ACID - PROSTAGLANDIN D2
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Transfere Grafic File
PG2_ideal.tgf
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Cell signaling Prostaglandins controlled processes:
1) constriction of muscle cells around blood vessels,
2) aggregation of platelets during blood clotting, and
3) constriction of the uterus during labor. Prostaglandins also
4) deliver and strengthen pain signals and 5)induce inflammation.
Almost all mammalian cells except erythrocytes produce one or more of eicosanoids,
Prostaglandins are created from and have a common precursor molecule Arachidonic Acid.
20-carbon omega=6 compound (Greek eikosil , "twenty") C20:4:
prostaglandins(PGs), prostacyclins (PGIs), thromboxanes (TXs), leukotrienes (LTs).
Prostaglandins: PGA2, PGE1, PGE2, PGE3, PGF2a, PGG2, PGH2
and Prostacyclin PGI2.
Thromboxanes TXA2 and TXB2 .
Leukotriene LTE4 .
(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid - arachidonic acid Back to the tutorial.
Transfere Grafic File ACD_ideal.tgf Integrated Scientific Information System deposit DATA:
Essential omega=6 unsaturated Fatty Acid Arachidonic Acid C20:4 with four unsaturated C=C bonds. Precursor of four Eicosanoids: Prostaglandins, Prostocyclines, Tromboxanes and Leukotrienes.
These five different Physiological processes
are all controlled by four different classes of prostaglandins-Eicosanoids:
Cell signaling Prostaglandins controlled processes:
1) constriction of muscle cells around blood vessels,
2) aggregation of platelets during blood clotting, and
3) constriction of the uterus during labor. Prostaglandins also
4) deliver and strengthen pain signals and 5)induce inflammation.
Almost all mammalian cells except erythrocytes produce one or more of eicosanoids,
Prostaglandins are created from and have a common precursor molecule Arachidonic Acid.
20-carbon omega=6 compound (Greek eikosil , "twenty") C20:4:
prostaglandins(PGs), prostacyclins (PGIs), thromboxanes (TXs), leukotrienes (LTs).
Prostaglandins: PGA2, PGE1, PGE2, PGE3, PGF2a, PGG2, PGH2
and Prostacyclin PGI2.
Thromboxanes TXA2 and TXB2 .
Leukotriene LTE4 .
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