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6 Hemostasis and Thrombosis
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G Lowe
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LEARNING OBJECTIVES
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After reading this chapter you should be able to:
  • Outline the sequential mechanisms involved in normal hemostasis.
  • Summarize the processes through which the vessel wall regulates hemostasis and thrombosis.
  • Describe the role of platelets in hemostasis and thrombosis.
  • Outline pathways through which antiplatelet drugs act.
  • Describe the pathways of blood coagulation, and how these are tested in the clinical hemostasis laboratory to identify coagulation disorders.
  • Describe the physiological inhibitors of blood coagulation.
  • Outline pathways through which anticoagulant drugs act.
  • Describe the main components of the fibrinolytic system.
  • Describe how thrombolytic (fibrinolytic) drugs act.
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