12 Carbohydrate Storage and Synthesis in Liver and Muscle
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After reading this chapter you should be able to:
- Describe the structure of glycogen.
- Identify the primary sites of glycogen storage in the body and the function of glycogen deposits in these tissues.
- Outline the metabolic pathways for synthesis and degradation of glycogen.
- Describe the mechanism by which glycogen is mobilized in liver in response to glucagon and in muscle during exercise and in response to epinephrine.
- Explain the origin and consequences of glycogen storage diseases in liver and muscle.
- Describe the mechanism for counter-regulation of glycogenolysis and glycogenesis in liver.
- Outline the pathway of gluconeogenesis, including substrates, unique enzymes and regulatory mechanisms.
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