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14 Oxidative Metabolism of Lipids in Liver and Muscle
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J W Baynes
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LEARNING OBJECTIVES
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After reading this chapter you should be able to:
  • Describe the pathway for activation and transport of fatty acids to the mitochondrion for catabolism.
  • Outline the sequence of reactions involved in oxidation of fatty acids in the mitochondrion.
  • Describe the general features of pathways for oxidation of unsaturated, odd-chain and branch-chain fatty acids.
  • Explain the rationale for the pathway of ketogenesis and identify the major intermediates and products of this pathway.
  • Describe the mechanism by which hormonal activation of lipolysis in adipose tissue is coordinated with activation of gluconeogenesis in liver during fasting.
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