14 Oxidative Metabolism of Lipids in Liver and Muscle
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After reading this chapter you should be able to:
- Describe the pathway for activation and transport of fatty acids to the mitochondrion for catabolism.
- Outline the sequence of reactions involved in oxidation of fatty acids in the mitochondrion.
- Describe the general features of pathways for oxidation of unsaturated, odd-chain and branch-chain fatty acids.
- Explain the rationale for the pathway of ketogenesis and identify the major intermediates and products of this pathway.
- Describe the mechanism by which hormonal activation of lipolysis in adipose tissue is coordinated with activation of gluconeogenesis in liver during fasting.
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