| 33 Control of Gene Expression
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After reading this chapter you should be able to:
- Describe the general mechanisms of regulation of gene expression, including the role of cis-acting promoters and enhancers and trans-acting transcription factors.
- Describe the many levels at which gene expression may be controlled, using steroid-induced gene expression as a model.
- Explain how alternate splicing, alternate promoters and post-transcriptional editing can modulate expression of a gene.
- Explain how the structure and packaging of chromatin can affect gene expression.
- Explain how genomic imprinting can result in changes in gene expression, depending on whether alleles are maternally or paternally inherited.
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