37 Biochemical Endocrinology
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After reading this chapter you should be able to:
- Describe the pathway and regulatory processes controlling the biosynthesis of thyroid hormones and the mechanism of their transport to and action on target tissues.
- Describe the pathway and mechanisms regulating synthesis and activity of glucocorticoids, from the hypothalamus to target organs.
- Outline the pathway and mechanisms regulating the synthesis and activity of sex steroid hormones and their role in regulation of male and female reproduction.
- Describe the direct and indirect actions of growth hormone, including the role of IGF-I.
- Outline the role of prolactin in reproduction.
- Describe the many and variable consequences of deficiencies and excesses of hormones regulated by the hypothalamo-pituitary axis.
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