| 41 Cell Growth, Differentiation, and Cancer
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After reading this chapter you should be able to:
- Define the stages of the mammalian cell cycle.
- Describe how growth factors regulate cell proliferation.
- Outline the regulation of cell cycle progression by cyclins and cyclin-dependent kinases.
- Discuss the regulation of apoptosis by caspases and Bcl-2 family members.
- Explain how deregulation of growth control leads to the development of tumors.
- Distinguish between oncogenes and tumor suppressor genes, and describe the roles they play in tumor progression.
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