Release Notes: MDL Chime Version 2.6 SP6

(c) Copyright 2004 MDL Information Systems, Inc.
All Rights Reserved.
March 2004

This document contains the Release Notes for: 

MDL Chime for Web (Plug-in) Version 2.6 SP6

This section provides information about MDL Chime for Web (plug-in):

  1. Introduction
  2. Bugs Fixed in Version 2.6 SP6
  3. Licensing Terms
  4. Support Matrix
  5. Installer Issues
  6. General Interaction with MDL ISIS/Draw
  7. Known Problems and Limitations
  8. JCAMP-DX Spectral display



    The MDL Chime plug-in displays 2D and 3D molecules directly within a web page and works with both Netscape and Microsoft browsers. The molecules in the web page are "live," meaning they are not just pictures, but chemical structures that can be rotated, reformatted, and saved in various file formats for use in modeling or database software. Anyone with a knowledge of HTML can add structures to their research projects, tutorials, newsletters, journals, and presentations published across an intranet or the Internet. If you are familiar with RasMol or CSML scripting, you can create very interactive web pages.


    • cct00045505 Chime/Chime Pro issues in Kanji environment
    • cct00039187 Amino acid sequence represented by group abbreviations has terminal groups stripped
    • cct00039188 Editing a amino acid sequence rendered using group abbreviations in ISIS/Draw causes the structure to be expanded
    • cct00034881 "Abbreviation is written as expanded structure in V3000 format" this applies to Chime
    • cct00046319 NMR Spectra in JCAMP format displays a different shift.
    • cct00048196 Refreshing multiple IE instances with multiple ChimePro structures gives initialization error
    • cct00048876 Atom-Click does not function in multiple windows

    MDL Chime is free for all users subject to the restrictions of the Chime license agreement. This agreement is available for download from the MDL Web site at the following URL MDL also provides Network and Distribution licenses.


    For general information about MDL Chime, please refer to the MDL Web site at the following URL:

    You are strongly encouraged to upgrade to the most recent point release of any web browser MDL Chime supports. 
    You can download the latest version of Internet Explorer at


    Please uninstall any previous versions of the Chime plugin via the 'Control Panel > Add/Remove Programs', before installing MDL Chime 2.6 SP6.

    The MDL Chime Installer by default looks in the Windows Registry for the locations of supported web browsers on your system. Using the Windows Registry is not a foolproof way for locating web browser installations. If using the Windows Registry doesn't work for you, please set the installer to either search your local drive(s) or explicitly specify your web browser location.

    You can set this option when the installer prompts you to select the method for finding the web browser. Microsoft Internet Explorer cannot work with local files unless the proper file types are registered. This is done automatically by the installer unless explicitly disabled by the user. If a desired file type is not registered, please rerun the Chime installer, or configure the MIME types manually:

    1. Open Windows Explorer
    2. Options (or View > Folder Options if you have Active Desktop enabled)
    3. Click the File Types tab to select it
    4. Click the New Type button to add a new file type

    The installer will attempt to replace an older version of Chime. The installer cannot replace Chime if the plug-in is currently in use by a web browser. Please exit all web browsers before installing Chime, and make sure there is no Chime structure on display on your Active Desktop if you are using Internet Explorer. The installer will place the following files on your system:

       npchime.dll     (plugins folder)
       (plugins folder, used for LiveConnect)
                        NOTE: Do not unzip this file
       chimepro.html   (plugins folder, the release notes for Chime)
       chime26.isu     (plugins folder, used to uninstall Chime)
       sculptapi.dll   (Windows System folder, used for Sculpt)
       ChimeShim.dll   (plugins folder, Internet Explorer only)	


    You can transfer MDL mol, rxn, tgf and skc files to ISIS/Draw 2.4 and later by either double clicking in the Chime window in 2D mode or by using Chime's Edit > Transfer to ISIS/Draw menu. Large molecules such as proteins will not transfer to ISIS/Draw, nor will they appear in Chime's 2D display mode.


    Unix, Linux and Macintosh Support
    The Chime plug-in is only supported on Windows 2000 and Windows XP.


    MDL has integrated JCAMP-DX reader and viewer capabilities into Chime using code licensed from the University of West Indies, Mona Jamaica. You can find additional information and documentation on JCAMP-DX at the following URL:

    JCAMP Spectra will not print on Netscape or Internet Explorer. This is a limitation with Chime. To print a Chime spectral display, you need to copy the image to an image editing program and print from that program. The steps are:

    1. Make sure the spectral image is in the front most window
    2. Press the Alt and Print Scrn keys on the keyboard at the same time
    3. Open an image editor such as MS Paint
    4. Select Paste on the Edit menu
    5. Edit the image if necessary
    6. Print the image from the image editor program

    Fourier Transformations are not supported by MDL Chime.

    JCAMP is supported only on the Windows platform.

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