Between 0-5 delta, OH and NH proton signals may appear.
The chemical shifts for these protons present special problems. An OH group map appear
nearly anywhere in the spectrum and the observed chemical shift is dependent on a number
of things such as concentration, solvent and trace impurities.
One method used for determining whether a peak is due to an OH group is that of deuterium
exchange. By treatment with D2O, the hydrogens often rapidly exchange and the peak then
disappears.
Hydrogens attached to nitrogen atoms may not show up at all in a spectrum or they may be
extremely broad and unresolved.
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Created December 1994. Last modified 10th July-97, rjl