Carboxypeptidase A (CPA) (enz)
(
E.C.3.4.17.1 )
CPA

CPA
complex with the slowly hydrolyzed substrate, 2-glycyl-L-tyrosine

Zn atom

5cpa.pdb
External Active SiteView
1.2.
Note Tyr 248 sidechain is position shifted.

Zn atom

3cpa.pdb
Enzyme Active Site
3.4.

Zinc Coordination Bonds
5..6.
 
HO-phenol-Tyr-Gly-NH3+
 |
 COO-

 

Zn

substrate N-terminus

substrate C-terminus
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Duane W. Sears
November 20, 1997