| GH has a wide range of actions in regulating growth and intermediary metabolism
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It is not surprising, in view of the wide range of actions of GH, that several factors other than GHRH and somatostatin can influence GH secretion. These include other hormones (estradiol ) and metabolic fuels (glucose). Several pharmacologic agents are also known to influence GH secretion. These factors act at the higher centers and the hypothalamus to alter the pattern of GHRH and somatostatin secretion.
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