The remainder of the page is organized by problem set number. Go to problem set materials for This Week. Select problem set number:   0   1   2   3   4   5   6   7   8   9   10   11   12.

Indicates linked material required for the course. Unmarked links correspond to optional/supplementary information.

PS #0: Review of (some) Quantitative Biochemistry Topics. The Graphs that accompany the answer sheet for this problem set. A page dealing with first-order decay and some practice kinetics problems.

PS #1: Protein and Nucleic Acid Structures: Graphics Display. Protein Structure Review Pages Amino Acid & Peptide Structures are viewed as Chime-generated images. Amino Acid Identification Quiz. Protein Architecture tutorial using Protein G as the example. RasMol Topics The CMU RasMol Tutorial is the on-line version of the tutorial written by Dr. David Hackney. The RasMol Manual: Frames is an online version of the v2.6 Manual. An annotated Example of a PDB file from the online RasMol manual. The links submitted for this problem set were added to the WWW Links page. Check your understanding of RasMol commands with an interactive RasMol Quiz.

PS #2: Protein Folding: Energetics & Design. Problem Set #2: Links & Files. Rop Protein Architecture: Chime display of a four-helix bundle protein.

PS #3: Activation of Ras GTPase by GAPs. Problem Set #3: Links & Files.

PS #4: Selective Inhibitors of Isozyme 2 of Cyclooxygenase. Problem Set #4: Links & Files.

PS #5: DNA & RNA Structures. The basics shown as Chime displays.       Overviews of DNA and RNA Structure: Side-by-side comparison.           B-DNA Structure: Additional details on bases and stacking.           A-RNA Structure: Additional details on bases and stacking. Eco RI-DNA Structure: Chime display of the protein-DNA complex.       Schematic Diagram of the Eco RI DNA site (for problem #1).       Potential H-bonds between a protein and DNA are shown as base pair overlays.

PS #6: Combinatorial Approaches to Collagenase Inhibitors.

PS #7: Ribosome Structure & mRNA Decoding. Problem Set #7: Links & Files.       Yeast tRNAPhe: A Chime & RasMol-scripted tour of the structure.

PS #8: Catalysis of Peptide Bond Formation by rRNA. Problem Set #8: Links & Files.

PS #9: Regulation of MAP Kinase in Development.

PS #10: Cooperativity of T7 DNA Helicase.

PS #11: Factors Influencing Stability of Coiled-coil Interactions.

PS #12: FtsZ as a Prokaryotic Tubulin.

Advanced Biochemistry at CMU.